Investing early in technologies and people
transforming mental and neuro health.

We believe mental and neuro health are among humanity’s most urgent challenges and greatest opportunities.
ֿֿWe back bold founders building breakthrough technologies that are reshaping the future of mental and neuro health, while generating attractive returns for our investors.
MISSION

We Don’t Bet on Trends. We Invest Ahead.

 

Mental and neuro health aren’t side problems. They’re the foundation of health, longevity, and well-being. And right now, that foundation is cracked.

  • Brain disorders account for 15% of the global disease burden
  • Mental and neuro health costs projected to reach $6T annually by 2030
  • Over 3.4 billion people are affected by mental and neurological conditions

 

This is a complex, growing crisis, one that demands more than medication.
It calls for a new approach. New tools. New thinking.

The next leap in human progress will begin by solving the challenges within our human operating system: mental, neuro, and behavioral health.

This is the beginning of a multi-decade transformation, not just in healthcare, but in how we live, connect, and experience life.

At Serendipity Impact VC, we back what it takes to get there.

APPROACH

Hands-On. High-Trust. Mitigating Risks.
Built to Outperform.

We help founders to turn breakthrough science into scalable, market-ready solutions for the hardest problems in mental and neuro health.

Invest Early

We join at the pre-seed and seed stages, where our involvement makes the greatest impact.

We’ve founded, scaled, and sold companies. We bring the know-how, a blend of experience, network, and expertise, to help our portfolio companies lay the foundation for long-term success.

Roll Up Our Sleeves

We’re co-pilots, not “write a check and wait” capital. From product roadmap and go-to-market to landing first customers, we work closely with founders to co-develop strategies and mitigate risks.

We build a network of clinicians, regulatory experts, market leaders, and we stay involved.
We mentor. We problem-solve. We celebrate wins together.
It’s unconventional, and it works. Previous fund returned 4.3x in two years.

Focus on Mental and Neuro

We invest exclusively in technological solutions for mental and neuro health. That’s it. This is a space we’re built to lead, and we’ve done it before.
We understand the markets, the regulatory landscape, the unmet needs, and the science. That's our edge and our founders leverage.

Israeli Origins, US Market

Our deal flow is proprietary, built on decades of deep trusted relationships across the Israeli innovation ecosystem.
We’re rooted in the U.S. market, with access to the networks, partners, and opportunities that matter. Where others advise from the sidelines, we guide founders through the noise, across oceans, and into the rooms that count.

TEAM

We’re Co-Pilots to Founders Building What’s Next.

From the people behind Visionsense (acquired by Medtronic), Joy Ventures (pioneered neuro-wellness), YU Innovation Lab (a borderless launchpad for Israeli startups in NYC), and HealthYA Ventures (4.3x return in 2 years), we don’t just write checks. 
We work alongside founders to build scalable solutions reshaping the future of mental and neuro health.

Avi Yaron

Co-Founder and Managing Partner, Israel

Neurotech pioneer, visionary investor, and serial entrepreneur with 30+ years of experience building, scaling, and exiting transformative HealthTech ventures.

Founder & CEO of Visionsense, a 3D surgical visualization company born from Avi’s personal battle with a life-threatening brain tumor.He invented the core technology, managed and scaled globally, revolutionizing minimally invasive neurosurgery. The company was acquired by Medtronic (NYSE: MDT) for $75M.

Co-founder & Managing Partner at HealthYA Ventures, a $50M early-stage HealthTech fund. Delivered a 4.3x return in just 2 years by applying deep domain expertise, disciplined operations, and a proprietary risk-mitigation framework.
Previously CEO of Joy Ventures, a $50M NeuroWellness VC fund. Former Lieutenant in Israel’s elite Unit 8200. TEDx speaker and member of the 8400 Health Network and IEF.
Education:
B.Sc. in Electrical Engineering, Tel Aviv University
MSM, Executive Management Program, Questrom School of Business, Boston University

Learn more about Avi:

Dr. Maria Blekher

Co-Founder and Managing Partner, NYC

Behavioral scientist, venture strategist, and entrepreneur with 15+ years of experience in U.S. go-to-market strategy and early-stage growth, with a focus on mental health innovation.
Founding Director of the YU Innovation Lab, a borderless NYC-based launchpad for early-stage Israeli and U.S. startups. Pioneered an academy-as-platform model that integrated academic infrastructure with private-sector partnerships and hands-on founder support to accelerate U.S. market entry.
Strategic advisor to mental health ventures including the MyWhat/If Foundation and MindGuard, and advisory board member at 97212 Ventures. A dedicated mentor to early-stage founders and longtime advocate for women in tech, Maria is a key connector in the Israeli–U.S. innovation ecosystem.
A recognized thought leader in mental health tech, she speaks regularly on the intersection of technology and the human experience, translating science into market-ready solutions for neuro and mental health challenges.
Ph.D. and MBA in Marketing and Consumer Behavior, Ben-Gurion University of the Negev
Former Visiting Scholar, NYU Stern School of Business

Joe Rollero

Growth Advisor, NYC

Commercial strategist and startup operator with 25+ years of experience scaling surgical technologies and navigating global healthcare markets.
Former commercial lead at Visionsense, where he helped drive global sales and go-to-market strategy from early-stage concept through its $75M acquisition by Medtronic. Post-acquisition, he led integration and international expansion of the company’s surgical visualization platform.
Founding Partner at Med-Connect360, advising high-growth medtech startups in robotics, MIS, and AI-powered surgical innovation. Previously held senior leadership roles at Johnson & Johnson, where he launched and scaled $100M+ surgical businesses and introduced new product lines in minimally invasive cardiac surgery.
Holds multiple patents in surgical technology. Focused on turning clinical innovation into commercial success.
B.S. in Business, Jacksonville University
Executive Education, Columbia Business School and UCLA Anderson

Amit Tobolsky

Investor Relations Director, SF

Marketing strategist and brand builder with a strong foundation in digital strategy, content development, and founder support across early-stage innovation and social impact sectors.
Founder & CEO of TOBO.CREATIVE, where he advises startups and growth-stage companies on brand positioning, integrated marketing campaigns, and go-to-market planning. Works directly with executive teams to uncover market opportunities through creative and data-driven strategy.
Previously led marketing strategy initiatives at the YU Innovation Lab, supporting over 70 international startups. Designed specialized programs and content strategies to drive audience engagement and expand U.S. market visibility.
Member of Grammy U at The Recording Academy, where he launched the first university chapter focused on emerging music industry talent through creative collaboration and community leadership.
B.S. in Digital Marketing & Strategy, magna cum laude, Sy Syms School of Business, Yeshiva University

PORTFOLIO

Bold founders. Deep tech. Multi-billion-dollar markets.

Transforming mental and neuro health, one breakthrough at a time.

CONNECT

Join Us on This Journey

We are building a consortium of forward-thinking LPs, partners, and innovators who share our passion for
transforming neuro and mental health. Whether you’re looking to invest, collaborate, or simply learn more,
we’d love to hear from you.